#pnasnexus

🧠 What If Alzheimer’s Starts Inside Brain Cells — Before the Plaques Take Over?

🧠 What If Alzheimer’s Starts Inside Brain Cells — Before the Plaques Take Over? For decades, Alzheimer’s disease has been strongly associated with amyloid beta plaques — sticky protein deposits that build up between neurons. This idea shaped an entire generation of drug development. But clearing p…