As reported in Science, the connection between the brain and body weakens with age, as does the 'communication' between…

As reported in Science, the connection between the brain and body weakens with age, as does the 'communication' between organs. Scientists suspect a causal link here. It's important to note that not only does the brain interact with various organs and tissues through innervation pathways, but the organs and tissues themselves—including the liver, intestines, heart, lungs, muscles, and even bones—also send signaling molecules to each other.

This inter-organ communication is essential for health and longevity—a concept gaining traction.

We recall about 15 years ago when A.M. Olovnikov proposed a "crazy" hypothesis to explain the course of evolution. He devised a mechanism to enhance evolvability, suggesting that different organs connected through the brain to the gametogenic tissue, sending signals to the sex cells. He published an article in "Biochemistry," which seemed pure fantasy at the time.

However, putting aside fantasies, various organs and tissues do communicate, for instance, during regeneration and wound healing. As biologists from Duke point out, regeneration is not a localized event but a process involving the entire body. Healthy tissues far from the injury site also participate.

This complex web of mutual connections gives rise to another "crazy" idea: treating a diseased organ by targeting another, healthy one. This idea can even be tested.